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Investor Announcement

Prana’s PBT434 Inhibits Accumulation of Parkinson’s protein and Subsequent Death of Brain Cells

Prana Biotechnology today announced that PBT434, Prana’s lead drug candidate for Parkinson’s disease (PD) and movement disorders, will be presented at two international conferences in March. The key finding to be reported is that PBT434 reduces the aggregation and accumulation of a key protein (alpha- synuclein) in multiple transgenic animal models of the disease.

Investor Announcement

Prana Announces that New York Academy of Sciences eBriefing available online

Prana Biotechnology today announced that the New York Academy of Sciences eBriefing which provides information and video footage of the symposium which took place on November 29th titled “Targeting Metals in Alzheimer’s and Other Neurodegenerative Diseases” is now available for viewing by the public by going to: www.nyas.org/MetalsandAD-eB. The eBriefing features multimedia presentations of speakers’ slides and audio, written meeting summary, and links to related resources.

Investor Announcement

Metal Hypothesis for Alzheimer’s, Huntington and other Neurodegenerative Diseases Declared Promising Therapeutic Strategy by Scientists at New York Academy of Sciences Symposium

Prana Biotechnology today announced that leading scientists discussing the Metal Hypothesis at the New York Academy of Sciences on November 29th at a symposium titled “Targeting Metals in Alzheimer’s and Other Neurodegenerative Diseases”, highlighted the promise that therapies like Prana’s PBT2 could offer for sufferers of neurodegenerative diseases.

Investor Announcement

Prana to present at New York Academy of Science Symposium on November 29th

Prana Biotechnology today announced that the New York Academy of Science is hosting a symposium on November 29th titled “Targeting Metals in Alzheimer’s and Other Neurodegenerative Diseases”. Dr. Rudy Tanzi, the Joseph P. and Rose F. Kennedy Professor of Neurology at Harvard University and Prana’s Chief Scientific Advisor, and Dr. Robert Cherny. Prana’s Head of Research, will take part in the symposium.

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