Professor Rudolph Tanzi
Chief Scientific Advisor, Scientific Co-Founder, Professor of Neurology, Harvard Medical School
Professor Tanzi is the co-founding scientist and Chief Scientific Adviser at Prana Biotechnology. Dr Tanzi is the Director of the Genetics and Aging Research Unit at the MassGeneral Institute for Neurodegenerative Diseases, and the Professor of Neurology at Harvard Medical School at Massachusetts General Hospital.
In 1980, Professor Tanzi was on the team with Dr. James Gusella that found the Huntington‘s disease gene and subsequently has found four genes that are implicated in familial Alzheimer‘s disease. Dr Tanzi has investigated the genetic causes of Alzheimer's disease since 1982, and co-discovered the three genes which cause early-onset familial Alzheimer’s disease.
In 1994, Dr Tanzi's laboratory discovered the crucial link between zinc and copper, and the formation of beta-amyloid, findings that were published in the journal Science.
Over the past eight years, much of Professor Tanzi‘s research has centered around two genes known as the “presenilins”, mutations which account for up to half of early-onset familial Alzheimer‘s disease.